Confirmation of the structure of tetra-O-(tert-butyldimethylsilyl)-D-glucono-1,4-lactone formed by silylation of D-glucono-1,5-lactone

Janak Singh; John DiMarco; Thomas P Kissick; Prashant Deshpande; Jack Z Gougoutas

doi:10.1016/s0008-6215(02)00014-9

Confirmation of the structure of tetra-O-(tert-butyldimethylsilyl)-D-glucono-1,4-lactone formed by silylation of D-glucono-1,5-lactone

Carbohydr Res. 2002 Mar 15;337(6):565-8. doi: 10.1016/s0008-6215(02)00014-9.

Authors

Janak Singh¹, John DiMarco, Thomas P Kissick, Prashant Deshpande, Jack Z Gougoutas

Affiliation

¹ Process Research and Development, Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543, USA. [email protected]

PMID: 11890895
DOI: 10.1016/s0008-6215(02)00014-9

Abstract

The structure of tetra-O-(tert-butyldimethylsilyl)-D-glucono-1,4-lactone made by the silylation of D-glucono-1,5-lactone has been confirmed by single-crystal X-ray analysis.

MeSH terms

Carbohydrate Conformation
Crystallography, X-Ray / methods
Gluconates / chemistry*
Lactones
Models, Molecular
Silicones / chemistry*
X-Ray Diffraction / methods

Substances

Gluconates
Lactones
Silicones
beta-glucono-1,5-lactone