Specific bone morphogenic protein receptor II mutations found in primary pulmonary hypertension cause different biochemical phenotypes in vitro

Chest. 2002 Mar;121(3 Suppl):83S.
No abstract available

MeSH terms

  • Animals
  • Bone Morphogenetic Protein Receptors, Type II
  • Bone Morphogenetic Proteins / metabolism*
  • Cell Line
  • Exons
  • Humans
  • Hypertension, Pulmonary / genetics*
  • Hypertension, Pulmonary / metabolism
  • Mice
  • Mutation*
  • Phenotype*
  • Protein Serine-Threonine Kinases / genetics*
  • Transforming Growth Factor beta / metabolism

Substances

  • Bone Morphogenetic Proteins
  • Transforming Growth Factor beta
  • Protein Serine-Threonine Kinases
  • BMPR2 protein, human
  • Bmpr2 protein, mouse
  • Bone Morphogenetic Protein Receptors, Type II