Blood concentration of milnacipran in a case of a fatal automobile accident

J Anal Toxicol. 2002 Mar;26(2):123-6. doi: 10.1093/jat/26.2.123.

Abstract

A fatal automobile accident involving milnacipran and ethyl alcohol is reported. The drug was identified and quantitated in blood by high-performance liquid chromatography-diode-array detection. The concentration of milnacipran in peripheral blood was 3.15 microg/mL exceeded 10.5 times the therapeutic concentration. The blood ethyl alcohol level was 1.3 g/L.

Publication types

  • Case Reports

MeSH terms

  • Accidents, Traffic*
  • Adult
  • Alcohol Drinking / adverse effects
  • Antidepressive Agents / adverse effects
  • Antidepressive Agents / blood*
  • Chromatography, High Pressure Liquid
  • Cyclopropanes / adverse effects
  • Cyclopropanes / blood*
  • Drug Interactions
  • Ethanol / adverse effects
  • Ethanol / blood
  • Fatal Outcome
  • Female
  • Forensic Medicine / methods
  • Humans
  • Milnacipran
  • Substance Abuse Detection / methods

Substances

  • Antidepressive Agents
  • Cyclopropanes
  • Ethanol
  • Milnacipran