Congenital multiple cavernous angiomas associated with thrombosed arteriovenous malformation of the brain--case report

Neurol Med Chir (Tokyo). 2002 Feb;42(2):67-72. doi: 10.2176/nmc.42.67.

Abstract

A 16-year-old girl presented with multiple cerebral cavernous angiomas with calcifications due to repeated hemorrhages and a thrombosed cerebral arteriovenous malformation (AVM). Her 18-year-old elder sister also had multiple cerebral cavernous angiomas associated with calcifications, which suggested presence of repeated previous hemorrhages. Surgical removal via a right occipital craniotomy resulted in a good outcome. The histological diagnosis was thrombosed AVM. Evaluation of congenital vascular anomaly needs to take into consideration the combination of other congenital vascular anomalies and their familial occurrence.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / genetics
  • Brain Neoplasms / surgery*
  • Cerebral Cortex / blood supply
  • Cerebral Cortex / pathology
  • Craniotomy
  • Diagnostic Imaging
  • Female
  • Hemangioma, Cavernous / diagnosis
  • Hemangioma, Cavernous / genetics
  • Hemangioma, Cavernous / surgery*
  • Humans
  • Intracranial Arteriovenous Malformations / diagnosis
  • Intracranial Arteriovenous Malformations / genetics
  • Intracranial Arteriovenous Malformations / surgery*
  • Intracranial Embolism / diagnosis
  • Intracranial Embolism / genetics
  • Intracranial Embolism / surgery*
  • Neoplasms, Multiple Primary / diagnosis
  • Neoplasms, Multiple Primary / genetics
  • Neoplasms, Multiple Primary / surgery*
  • Pedigree