Intraoperative micro- and macrostimulation of the subthalamic nucleus in Parkinson's disease

Mov Disord. 2002:17 Suppl 3:S155-61. doi: 10.1002/mds.10158.

Abstract

Studying the clinical effects induced by electrical stimulation of the subthalamic nucleus (STN) area in a parkinsonian patient under local anesthesia is a mandatory step to determine the precise location of the final chronic electrode. Using multiple microelectrodes, preferably in a concentric parallel array allows a precise mapping of the STN region. The most reliable features to determine the suitable target are stimulation-induced dyskinesias and rigidity decrease at a low intensity without adverse effects or only at far higher intensities. New skills are needed to assess all stimulation-induced effects and interpret them in anatomo-functional terms.

Publication types

  • Review

MeSH terms

  • Brain Mapping / instrumentation
  • Brain Mapping / methods
  • Electric Stimulation Therapy
  • Humans
  • Microelectrodes
  • Monitoring, Intraoperative / instrumentation
  • Neurons / physiology
  • Parkinson Disease / physiopathology
  • Parkinson Disease / surgery*
  • Parkinson Disease / therapy
  • Stereotaxic Techniques*
  • Subthalamic Nucleus / physiopathology
  • Subthalamic Nucleus / surgery*