Abstract
A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Case-Control Studies
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Child
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Diabetes Mellitus, Type 1 / epidemiology
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Diabetes Mellitus, Type 1 / genetics*
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Female
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Gene Frequency
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Genetic Predisposition to Disease
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Haplotypes
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Humans
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Interleukin-12 / genetics*
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Italy / epidemiology
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Male
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Polymorphism, Genetic*
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Risk Factors