In vitro antimicrobial activity of 3,4-dihydro-s-triazinobenzimidazole derivatives

G Gulyás; T Emri; A Simon; Z Györgydeák

doi:10.1007/BF02818561

In vitro antimicrobial activity of 3,4-dihydro-s-triazinobenzimidazole derivatives

Folia Microbiol (Praha). 2002;47(1):29-31. doi: 10.1007/BF02818561.

Authors

G Gulyás¹, T Emri, A Simon, Z Györgydeák

Affiliation

¹ Department of Organic Chemistry, Faculty of Science, University of Debrecen, 4010 Debrecen, Hungary.

PMID: 11980265
DOI: 10.1007/BF02818561

Abstract

Among 31 3,4-dihydro-s-triazinobenzimidazole derivatives tested 12 compounds showed in vitro antimicrobial activity against G+ bacteria. Best results were obtained with substances containing naphthyl or halogenated phenyl group on the triazine ring. The tested derivatives had no significant in vitro antimicrobial activity against either the used G- species or fungi.

MeSH terms

Anti-Bacterial Agents
Anti-Infective Agents / chemistry
Anti-Infective Agents / pharmacology*
Benzimidazoles / chemistry
Benzimidazoles / pharmacology*
Fungi / drug effects*
Gram-Negative Bacteria / drug effects*
Gram-Positive Bacteria / drug effects*
Microbial Sensitivity Tests
Triazines / chemistry

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Benzimidazoles
Triazines