Fat targets for insulin signaling

Mol Cell. 2002 Apr;9(4):695-6. doi: 10.1016/s1097-2765(02)00509-9.

Abstract

Adipose cells control flux of fatty acids to peripheral tissues by storing and hydrolyzing triglyceride under hormonal control. New data reveal that insulin may regulate this process in part by promoting membrane trafficking of intracellular fatty acid transporters FATP1 and FATP4 to the plasma membrane.

Publication types

  • Review

MeSH terms

  • Adipocytes / drug effects
  • Adipocytes / physiology*
  • CD36 Antigens
  • Fatty Acid Transport Proteins
  • Fatty Acids / metabolism*
  • Humans
  • Insulin / physiology*
  • Membrane Glycoproteins / metabolism
  • Organic Anion Transporters / metabolism

Substances

  • CD36 Antigens
  • Fatty Acid Transport Proteins
  • Fatty Acids
  • Insulin
  • Membrane Glycoproteins
  • Organic Anion Transporters
  • Slc27a4 protein, mouse