Research progress in the stimulatory inputs regulating growth hormone (GH) secretion

Comp Biochem Physiol B Biochem Mol Biol. 2002 May;132(1):141-50. doi: 10.1016/s1096-4959(01)00544-9.

Abstract

A review is presented on progress in the research of stimulatory inputs that regulate growth hormone secretion, including recent results on the action of the hypothalamic peptides growth-hormone releasing factor (GHRH) and pituitary adenylate cyclase-activating polypeptide (PACAP), as well as that of both peptidic (growth hormone-releasing hexapeptide; GHRP-6) and non-peptidyl (L-163,255) synthetic GHSs on somatotrope cell function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Growth Hormone / metabolism*
  • Growth Hormone-Releasing Hormone / metabolism*
  • Models, Biological
  • Neuropeptides / metabolism*
  • Oligopeptides / metabolism*
  • Peptides / chemistry
  • Piperidines / metabolism*
  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Signal Transduction
  • Spiro Compounds / metabolism*
  • Swine

Substances

  • Neuropeptides
  • Oligopeptides
  • Peptides
  • Piperidines
  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Spiro Compounds
  • L 163255
  • growth hormone releasing hexapeptide
  • Growth Hormone
  • Growth Hormone-Releasing Hormone