Breast cancer: regional blood flow and blood volume measured with magnetic susceptibility-based MR imaging--initial results

Radiology. 2002 May;223(2):558-65. doi: 10.1148/radiol.2232010428.

Abstract

The purpose of this study was to quantify microcirculation in breast neoplasms with magnetic susceptibility-based contrast material-enhanced magnetic resonance imaging. With this imaging method for invasive cancers, the mean values of the ratios of tumor to normal blood flow and blood volume were significantly higher (P <.002) than those for benign or normal tissue. The method allows independent measurement of regional blood flow and blood volume in breast cancers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Analysis of Variance
  • Blood Volume
  • Breast Neoplasms / blood supply*
  • Breast Neoplasms / pathology*
  • Contrast Media
  • Echo-Planar Imaging*
  • Female
  • Humans
  • Linear Models
  • Microcirculation
  • Middle Aged
  • Prospective Studies
  • Regional Blood Flow

Substances

  • Contrast Media