Clear cell myomelanocytic tumor of the thigh: report of a unique case

Am J Surg Pathol. 2002 Jun;26(6):809-12. doi: 10.1097/00000478-200206000-00018.

Abstract

The clear cell myomelanocytic tumor (CCMMT) is a recently reported and very rare member of the perivascular epithelioid cell family of tumors (PEComa). All CCMMTs reported to date have occurred in or immediately adjacent to the falciform ligament/ligamentum teres. We report a case of CCMMT that occurred in the right thigh of a 43-year-old woman. Histologic examination showed the classic features of CCMMT, and immunohistochemical studies confirmed co-expression of smooth muscle actin, HMB-45, and microphthalmia transcription factor.

Publication types

  • Case Reports

MeSH terms

  • Actins / metabolism
  • Adult
  • Angiomyolipoma / pathology
  • Antigens, Neoplasm
  • Biomarkers, Tumor
  • DNA-Binding Proteins / metabolism
  • Diagnosis, Differential
  • Epithelioid Cells / metabolism
  • Epithelioid Cells / pathology*
  • Female
  • Foam Cells / pathology
  • Humans
  • Immunohistochemistry
  • Melanocytes / metabolism
  • Melanocytes / pathology*
  • Melanoma-Specific Antigens
  • Microphthalmia-Associated Transcription Factor
  • Muscle Neoplasms / metabolism
  • Muscle Neoplasms / pathology*
  • Muscle Neoplasms / surgery
  • Neoplasm Proteins / metabolism
  • Sarcoma / metabolism
  • Sarcoma / pathology*
  • Sarcoma / surgery
  • Transcription Factors*

Substances

  • Actins
  • Antigens, Neoplasm
  • Biomarkers, Tumor
  • DNA-Binding Proteins
  • MITF protein, human
  • Melanoma-Specific Antigens
  • Microphthalmia-Associated Transcription Factor
  • Neoplasm Proteins
  • Transcription Factors