Abstract
Three new diacetylenes (1, 4, 6) have been isolated as cytotoxic constituents from the methanolic extract of the stony coral Montipora sp. The structures have been elucidated on the basis of spectroscopic evidence. The compounds were evaluated for cytotoxicity against a small panel of human tumor cell lines and showed moderate to significant activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylene / analogs & derivatives*
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Acetylene / chemistry
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Acetylene / pharmacology
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Animals
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Anthozoa / chemistry*
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / isolation & purification
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Artemia
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Drug Screening Assays, Antitumor
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Humans
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Magnetic Resonance Spectroscopy
Substances
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Antineoplastic Agents
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Acetylene