Cloning and molecular characterization of the cDNA encoding histone H1 from Leishmania braziliensis

J Parasitol. 2002 Feb;88(1):199-203. doi: 10.1645/0022-3395(2002)088[0199:CAMCOT]2.0.CO;2.

Abstract

The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular / methods*
  • DNA, Complementary / genetics
  • DNA, Protozoan / analysis
  • DNA, Protozoan / genetics
  • Histones / chemistry
  • Histones / genetics*
  • Histones / metabolism
  • Leishmania braziliensis / genetics*
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA, Complementary
  • DNA, Protozoan
  • Histones

Associated data

  • GENBANK/AF131892