Decreased bone mineral density during GnRH analog therapy and polymorphism of estrogen receptor gene in precocious puberty

Endocr J. 1999 Mar:46 Suppl:S55-7. doi: 10.1507/endocrj.46.suppl_s55.
No abstract available

MeSH terms

  • Bone Density / drug effects*
  • Buserelin / pharmacology*
  • Child
  • Child, Preschool
  • Female
  • Gonadotropin-Releasing Hormone / adverse effects*
  • Gonadotropin-Releasing Hormone / analogs & derivatives*
  • Gonadotropin-Releasing Hormone / therapeutic use
  • Humans
  • Leuprolide / pharmacology*
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • Puberty, Precocious / drug therapy*
  • Puberty, Precocious / genetics
  • Puberty, Precocious / metabolism
  • Receptors, Estrogen / genetics*

Substances

  • Receptors, Estrogen
  • Gonadotropin-Releasing Hormone
  • LHRH, Ala(6)-Gly(10)-ethylamide-
  • Leuprolide
  • Buserelin