We present a rare and severe complication of condom. A 78-year-old man of dementia and neuropathic voiding dysfunction were sent to our Emergency Room due to loss of consciousness. Preliminary examinations showed only tachycardia and hypotension that revealed a condition of septic shock. The abnormal laboratory examinations revealed leukocytosis and deteriorated liver and renal function. Urinalysis was unable to be collected at emergency room because it was difficult to indwell the Foley catheter. The penis looked more than twice normal length. Strong parenteral antibiotics were given after blood culturing with removal of the condom. After debridement, the catheterization was successful. The circumcised wound healed gradually post-operation. However, he died 5 days later because of his severe urosepsis.