Ventricular tachycardia following ingestion of a commonly used antihistamine

Med J Aust. 2002 May 6;176(9):429-30. doi: 10.5694/j.1326-5377.2002.tb04485.x.

Abstract

This report describes ventricular tachycardia, likely to have been torsade de pointes, following ingestion of the non-sedating antihistamine loratadine. Documentation of the arrhythmia was made possible by the automatic electrogram storage facility of an implanted defibrillator in a patient with no prior history of cardiac arrhythmia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Defibrillators, Implantable
  • Female
  • Histamine H1 Antagonists / adverse effects*
  • Humans
  • Loratadine / adverse effects*
  • Tachycardia, Ventricular / chemically induced*
  • Torsades de Pointes / chemically induced

Substances

  • Histamine H1 Antagonists
  • Loratadine