A direct comparison of noninvasive coronary angiography by electron beam tomography and navigator-echo-based magnetic resonance imaging for the detection of restenosis following coronary angioplasty

Invest Radiol. 2002 Jul;37(7):386-92. doi: 10.1097/00004424-200207000-00005.

Abstract

Rationale and objectives: To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA).

Methods: One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent). MRI was performed using respiratory-gated sequences (24-48 cross-sections, 2-mm slice thickness, 20 mL Gd-DTPA). EBT and MRI images were evaluated concerning high-grade post-PTCA restenosis (> or = 70%) and validated against coronary angiography.

Results: In EBT, 28 patients and in MRI, 31 patients were not evaluable. In the remaining patients, sensitivity for restenosis detection was 90% in EBT (17/19) and 73% in MRI (11/15; P = 0.370). In EBT, specificity was significantly higher (66% vs. 49%, P = 0.043). Overall accuracy was 71% for EBT and 53% for MRI (P = 0.014).

Conclusions: For the detection of high-grade restenosis after PTCA, EBT demonstrated significantly higher accuracy than MRI.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angioplasty, Balloon, Coronary*
  • Contrast Media
  • Coronary Angiography*
  • Coronary Restenosis / diagnosis*
  • Female
  • Gadolinium DTPA
  • Humans
  • Imaging, Three-Dimensional
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed

Substances

  • Contrast Media
  • Gadolinium DTPA