[Outbreak of human rotavirus infection in an adult community]

Orv Hetil. 2002 Jun 2;143(22):1347-52.
[Article in Hungarian]

Abstract

Introduction: Group A rotaviruses are known as the major cause of severe dehydrating diarrhoea in infants.

Aims: In adults, the rotavirus infections are usually asymptomatic. In the present study the authors report a group A rotavirus outbreak in a psychiatric nursing home for adults.

Results: The outbreak lasted 3 weeks; the attack rate was 20%. The mean age of patients was 39 y (range 21 to 65; n = 25). The symptoms were mild, and most of the patients recovered within 2 or 3 days. The epidemiological data suggested that the virus was introduced by a patient, and it was transmitted by person-to-person route. Rotavirus positive specimens were characterised by serotyping and electropherotyping. The serotype-specific monoclonal antibody immunoassay demonstrated the circulation of a common strain with G1 specificity. These samples shared identical genome profile with strains circulated in the paediatric communities of the country.

Conclusion: In Hungary, this is the first published gastroenteritis outbreak among adults caused by group A rotaviruses with G1 serotype specificity.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Antibodies, Monoclonal
  • Diagnosis, Differential
  • Disease Outbreaks*
  • Female
  • Gastroenteritis / diagnosis
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology*
  • Humans
  • Hungary / epidemiology
  • Immunoassay / methods
  • Male
  • Mental Disorders* / complications
  • Middle Aged
  • Nursing Homes* / statistics & numerical data
  • Rotavirus / classification
  • Rotavirus / immunology
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / diagnosis
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / virology
  • Serotyping

Substances

  • Antibodies, Monoclonal