Abstract
We report that early chemosensitivity, defined by a greater than 50% reduction of M-component and plasma-cell marrow infiltration, after 2 cycles of VAD was correlated with a favorable outcome following autologous stem cell transplantation in 46 patients with newly diagnosed multiple myeloma submitted to high-dose therapy.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Cytarabine / administration & dosage
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Dexamethasone / administration & dosage
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Humans
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Multiple Myeloma / diagnosis
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Multiple Myeloma / mortality*
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Multiple Myeloma / therapy*
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Prognosis
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Retrospective Studies
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Stem Cell Transplantation*
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Survival Analysis
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Time Factors
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Transplantation, Autologous
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Treatment Outcome
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Vincristine / administration & dosage
Substances
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Cytarabine
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Vincristine
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Dexamethasone