Low-molecular-weight heparin for vertebral artery dissection

Clin Appl Thromb Hemost. 2002 Apr;8(2):179-81. doi: 10.1177/107602960200800215.

Abstract

A case of vertebral artery dissection and consequent basilar artery thrombosis in a 6-year-old patient is reported. The patient was treated with subcutaneous low-molecular-weight heparin at therapeutic doses (enoxaparin, 100 IU/kg twice daily) for 3 weeks, then reduced to 2,000 IU/day for 3 more weeks. After this time a magnetic resonance angiogram was obtained that showed complete recanalization of the left basilar artery. Enoxaparin proved to be a safe and useful therapy for thrombosis accompanying vertebral artery dissection.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Enoxaparin / administration & dosage
  • Heparin, Low-Molecular-Weight / administration & dosage*
  • Humans
  • Male
  • Thrombosis / drug therapy
  • Thrombosis / etiology
  • Treatment Outcome
  • Vertebral Artery Dissection / complications
  • Vertebral Artery Dissection / drug therapy*

Substances

  • Enoxaparin
  • Heparin, Low-Molecular-Weight