Abstract
This is the first report demonstrating the in vitro inhibitory activity of two novel microbicides (cellulose sulfate and polystyrene sulfonate) against bacterial vaginosis (BV)-associated bacteria. Vaginal application of these microbicides not only may reduce the risk of acquisition of human immunodeficiency virus and other sexually transmitted infection-causing organisms but may also decrease the incidence of BV.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents
-
Anti-Infective Agents / pharmacology*
-
Bacteria, Anaerobic / drug effects*
-
Bacteria, Anaerobic / growth & development
-
Cellulose / analogs & derivatives*
-
Cellulose / pharmacology*
-
Diffusion
-
Female
-
Gardnerella vaginalis / drug effects*
-
Gardnerella vaginalis / growth & development
-
Humans
-
Microbial Sensitivity Tests
-
Polystyrenes / pharmacology*
-
Vaginosis, Bacterial / microbiology*
Substances
-
Anti-Bacterial Agents
-
Anti-Infective Agents
-
Polystyrenes
-
polystyrene sulfonic acid
-
Cellulose
-
cellulose sulfate