Reactivation of retinal toxoplasmosis despite evidence of immune response to highly active antiretroviral therapy

Clin Infect Dis. 2002 Aug 15;35(4):e37-9. doi: 10.1086/341306. Epub 2002 Jul 19.

Abstract

We report a case of retinal toxoplasmosis that occurred in a patient with acquired immunodeficiency syndrome who had a previous diagnosis of cerebral toxoplasmosis, despite the patient having had a robust immune response to highly active antiretroviral therapy. Clinical decisions about whether to discontinue secondary prophylaxis for opportunistic infections continue to be challenging.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / immunology
  • AIDS-Related Opportunistic Infections / parasitology*
  • Adult
  • Antiretroviral Therapy, Highly Active
  • HIV Infections / complications
  • HIV Infections / drug therapy
  • HIV Infections / immunology*
  • Humans
  • Male
  • Retinal Diseases / etiology
  • Retinal Diseases / immunology
  • Retinal Diseases / parasitology*
  • Toxoplasmosis / etiology
  • Toxoplasmosis / immunology*