Older adults with acute myeloid leukemia

Curr Oncol Rep. 2002 Sep;4(5):403-9. doi: 10.1007/s11912-002-0034-y.

Abstract

Acute myeloid leukemia (AML) occurs most frequently in older adults, with a median age range from 65 to 70 years. Both the disease and its treatment are distinct from their counterparts in young patients. Herein we characterize the intrinsic biologic features of AML as it occurs in the older population, review currently available therapeutic approaches, and discuss therapeutic strategies in development.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Age Factors
  • Aged
  • Aging*
  • Antibiotics, Antineoplastic / therapeutic use
  • Antimetabolites, Antineoplastic / therapeutic use
  • Antineoplastic Agents / therapeutic use*
  • Cytarabine / therapeutic use
  • Drug Tolerance
  • Growth Substances / therapeutic use
  • Humans
  • Leukemia, Myeloid / drug therapy*
  • Recurrence
  • Remission Induction

Substances

  • Antibiotics, Antineoplastic
  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents
  • Growth Substances
  • Cytarabine