Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy

N Engl J Med. 2002 Aug 8;347(6):452-3. doi: 10.1056/NEJM200208083470619.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Alemtuzumab
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Antibodies, Neoplasm / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Chromosome Deletion
  • Chromosomes, Human, Pair 17 / genetics
  • Female
  • Genes, p53*
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics
  • Point Mutation
  • Remission Induction
  • Risk Factors

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antibodies, Neoplasm
  • Antineoplastic Agents
  • Alemtuzumab