Multislice computed tomographic angiography (MSCTA) is a versatile technique that combines speed, excellent contrast, superb spatial resolution, and extreme simplicity. It has a wide range of applications in the abdomen including all vascular pathologies, occlusive or dilative, with excellent demonstration of atherosclerotic plaques in large or smaller branches. MSCTA is the method of choice in the follow-up of patients undergoing endovascular procedures for aneurysms. It provides excellent results in assessing vascular involvement by neoplasms arising from the liver, biliary tract, pancreas, kidneys, and all other abdominal organs. MSCTA can be used successfully in potential living donors and in the follow-up of recipients. Although MSCTA is a brand new technique, several developments are under investigation, which should allow further advancements in speed and spatial resolution.