A new cycloamphilectene metabolite from the Vanuatu sponge Axinella sp

L Ciasullo; A Cutignano; A Casapullo; R Puliti; C A Mattia; C Debitus; R Riccio; L Gomez-Paloma

doi:10.1021/np010666m

A new cycloamphilectene metabolite from the Vanuatu sponge Axinella sp

J Nat Prod. 2002 Aug;65(8):1210-2. doi: 10.1021/np010666m.

Authors

L Ciasullo¹, A Cutignano, A Casapullo, R Puliti, C A Mattia, C Debitus, R Riccio, L Gomez-Paloma

Affiliation

¹ Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA), Italy.

PMID: 12193036
DOI: 10.1021/np010666m

Abstract

A new diterpene, N-formyl-7-amino-11-cycloamphilectene (1), was isolated from the apolar extract of the Vanuatu sponge Axinella sp. The structure and relative stereochemistry were established by spectroscopic and single-crystal X-ray studies.

MeSH terms

Animals
Chromatography, High Pressure Liquid
Crystallography, X-Ray
Diterpenes / chemistry
Diterpenes / isolation & purification*
Molecular Conformation
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Porifera / chemistry*
Stereoisomerism
Vanuatu

Substances

Diterpenes
N-formyl-7-amino-11-cycloamphilectene