Cytomegalovirus-induced glomerular vasculopathy in renal allografts: a report of two cases

Am J Transplant. 2002 Aug;2(7):684-8. doi: 10.1034/j.1600-6143.2002.20717.x.

Abstract

Cytomegalovirus (CMV) remains a major viral pathogen complicating renal transplantation. Tubulointerstitial nephritis is the commonly acknowledged and well-characterized pathologic feature of renal allograft CMV disease. There is controversy about whether there is a distinct entity as a CMV glomerulopathy in the absence of tubulointerstitial disease. We describe two patients with renal allograft dysfunction who displayed distinct features of CMV glomerular vasculopathy, in the absence of overt viral cytopathic changes involving the tubules.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antibodies, Viral / analysis
  • Cytomegalovirus / immunology
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Infections / pathology*
  • Humans
  • Kidney Glomerulus / pathology*
  • Kidney Glomerulus / virology
  • Kidney Transplantation / pathology*
  • Male
  • Middle Aged
  • Postoperative Complications / pathology*
  • Postoperative Complications / virology

Substances

  • Antibodies, Viral