Hypouricaemia as a marker of a generalized proximal tubular damage in alcoholic patients

Alcohol Alcohol. 2002 Sep-Oct;37(5):472-4. doi: 10.1093/alcalc/37.5.472.

Abstract

Aims and methods: Hypouricaemia is not frequently encountered in alcoholic patients. Described herein is the case of a 69-year-old alcoholic patient.

Results: The patient presented with severe hypouricaemia (serum uric acid 95.2 micro mol/l) due to renal urate wasting associated with a cluster of other metabolic abnormalities in the context of a reversible generalized dysfunction of the proximal tubules that mimicked Fanconi syndrome.

Conclusions: The underlying mechanisms of this rare presentation are discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alcoholism / blood*
  • Humans
  • Kidney Diseases / blood
  • Kidney Tubules, Proximal / metabolism
  • Kidney Tubules, Proximal / pathology*
  • Male
  • Uric Acid / blood*

Substances

  • Uric Acid