Total and subtotal aortic replacement for extensive aortic dissection in patients with or without Marfan's syndrome

Jpn J Thorac Cardiovasc Surg. 2002 Aug;50(8):315-20. doi: 10.1007/BF03032623.

Abstract

Objectives: Extensive aortic dissection with multiple entries often found in Marfan's syndrome patients ultimately requires replacement of the whole aorta. We present a surgical strategy and results for total and subtotal aortic replacement.

Methods: Subjects were 18 patients, including 14 Marfan's patients undergoing total (n = 13) or subtotal (excluding aortic arch) aortic replacement (n = 5), for DeBakey type I aortic dissection (n = 13) and DeBakey type IIIb aortic dissection with annuloaortic ectasia (n = 5) between February 1991 and April 2001. Mean age was 39.9 +/- 0.8 years--34.9 +/- 6.6 years in Marfan's patients vs. 57.7 +/- 4.7 years in non-Marfan patients. All operations were staged, with the mean number required per patient 3.1 +/- 0.8.

Results: Early mortality was 0% and late mortality 11% (2 of 18). Paraplegia or paraparesis occurring in 11%. Except for these patients, all current survivors enjoy good quality of life.

Conclusions: Total and subtotal aortic replacement for extensive aortic dissection may decrease mortality due to rupture or associated disease.

MeSH terms

  • Adult
  • Aorta / surgery
  • Aortic Aneurysm / surgery*
  • Aortic Dissection / surgery*
  • Blood Vessel Prosthesis*
  • Female
  • Humans
  • Male
  • Marfan Syndrome / complications*
  • Middle Aged