Screening for retinopathy of prematurity

Br J Ophthalmol. 2002 Oct;86(10):1127-30. doi: 10.1136/bjo.86.10.1127.

Abstract

Aim: A cross sectional (prevalence) study was performed to assess the usefulness and sensitivity of commonly employed criteria to identify infants for routine ophthalmoscopic screening for retinopathy of prematurity (ROP).

Methods: At a tertiary care centre between 1 January 1992 and 30 June 1998, experienced vitreoretinal specialists screened 438 premature infants for ROP. Retinal maturity and the presence of ROP were determined by indirect ophthalmoscopic examinations.

Results: Of the eligible infants surviving 28 days, 276 (91.7%) of 301 infants with birth weights </=1500 g and 162 (52.3%) of 310 infants with birth weights between 1501 and 2500 g were screened for ROP. 10 (3.9%) of the 310 infants with larger birth weights developed stage 1 or 2 ROP. Two (0.6%) of the 310 infants with larger birth weights developed stage 3 ROP. These two infants progressed to threshold ROP and required treatment.

Conclusions: Relatively restrictive criteria to identify premature infants eligible for routine ophthalmoscopic screening for ROP may be the cause for some infants going unexamined and their ROP undetected.

Publication types

  • Case Reports

MeSH terms

  • Birth Weight
  • Cross-Sectional Studies
  • Diseases in Twins
  • Gestational Age
  • Humans
  • Infant
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Neonatal Screening / methods*
  • Practice Guidelines as Topic / standards
  • Retinopathy of Prematurity / diagnosis*
  • Retrospective Studies
  • Time Factors