New diarylheptanoids from the stems of Carpinus cordata

J Nat Prod. 2002 Sep;65(9):1367-70. doi: 10.1021/np020048l.

Abstract

Two new diarylheptanoids, carpinontriols A (1) and B (2), were isolated from the stems of Carpinus cordata, along with the known diarylheptanoid, casuarinondiol (3), and five known compounds, (+)-catechin (4), methyl gallate (5), methyl gallate 3-O-beta-D-glucopyranoside (6), methyl gallate 4-O-beta-D-glucopyranoside (7), and methyl gallate 3-O-beta-D-(6'-O-galloyl)-glucopyranoside (8). The structures of 1 and 2 were elucidated by spectral methods. Among the isolated compounds, compounds 4-6 and 8 showed radical-scavenging activity in the DPPH assay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Betulaceae / chemistry*
  • Biphenyl Compounds
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Inhibitory Concentration 50
  • Korea
  • Models, Chemical
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Picrates
  • Plant Stems / chemistry
  • Polycyclic Aromatic Hydrocarbons / chemistry
  • Polycyclic Aromatic Hydrocarbons / isolation & purification*
  • Polycyclic Aromatic Hydrocarbons / pharmacology
  • Spectroscopy, Fourier Transform Infrared
  • Stereoisomerism

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Picrates
  • Polycyclic Aromatic Hydrocarbons
  • carpinontriol A
  • carpinontriol B
  • 1,1-diphenyl-2-picrylhydrazyl