Abstract
Antibiotic resistance of urinary tract pathogens has increased worldwide. Our aim was to provide information regarding resistance patterns of Escherichia coli in urinary tract infections (UTIs) and E. coli bacteraemia in Denmark. The overall resistance ranged from: ampicillin 20-47%, mecillinam 0-7%, trimethoprim 10-28%, sulfamethizole 22-47% and nitrofurantoin 0-3%. In strains with sulfamethizole MICs > 2048 mg/L, 97% carried sulI, sulII or both genes, with sulII being the most common. Among the sulI gene-positive strains, 96% were intI 1 gene positive.
MeSH terms
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Adolescent
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Adult
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Bacteremia / drug therapy
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Bacteremia / epidemiology
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Bacteremia / genetics
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Bacteremia / microbiology*
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Bacterial Proteins*
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Carrier Proteins / genetics*
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Community-Acquired Infections / drug therapy
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Community-Acquired Infections / epidemiology
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Community-Acquired Infections / genetics
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Community-Acquired Infections / microbiology
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Cross Infection / drug therapy
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Cross Infection / epidemiology
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Cross Infection / genetics
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Cross Infection / microbiology
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Denmark / epidemiology
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Drug Resistance, Bacterial / genetics*
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Escherichia coli / drug effects
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Escherichia coli / genetics*
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Escherichia coli / isolation & purification
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Female
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Humans
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Middle Aged
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Saccharomyces cerevisiae Proteins / genetics*
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Sulfonamides / pharmacology*
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Sulfonamides / therapeutic use
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Transcription Factors / genetics*
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Urinary Tract Infections / drug therapy
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Urinary Tract Infections / epidemiology
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Urinary Tract Infections / genetics
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Urinary Tract Infections / microbiology*
Substances
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Bacterial Proteins
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Carrier Proteins
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FZF1 protein, S cerevisiae
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Saccharomyces cerevisiae Proteins
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Sul2 protein, bacteria
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Sulfonamides
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Transcription Factors