Abstract
Follicular mycosis fungoides (FMF) is a rare cutaneous T cell lymphoma characterized by an atypical lymphoid infiltrate spreading within and around hair follicles without epidermotropism or follicular mucin deposits. Its occasional presentation with minimal epidermal involvement and/or follicular mucinosis suggests the need for uniform histologic criteria. We describe a new case of FMF associated with follicular mucinosis and discuss its morphologic spectrum of presentation.
MeSH terms
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CD3 Complex / analysis
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CD4 Antigens / analysis
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DNA, Neoplasm / analysis
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Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor / genetics
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Humans
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Immunohistochemistry
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Male
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Middle Aged
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Mucinosis, Follicular / complications
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Mucinosis, Follicular / genetics
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Mucinosis, Follicular / pathology*
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Mycosis Fungoides / complications
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Mycosis Fungoides / genetics
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Mycosis Fungoides / pathology*
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Polymerase Chain Reaction
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Skin Neoplasms / complications
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Skin Neoplasms / genetics
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Skin Neoplasms / pathology*
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T-Lymphocytes, Helper-Inducer / chemistry
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T-Lymphocytes, Helper-Inducer / pathology
Substances
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CD3 Complex
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CD4 Antigens
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DNA, Neoplasm