We report percutaneous coronary intervention performed on a lesion located in a sequential radial artery graft anastomosed to the descending aorta, distal circumflex artery and obtuse marginal artery. Coronary angiography revealed an 80% stenosis in the mid-segment of the sequential radial artery graft. Conventional balloon angioplasty was performed through the proximal anastomosis at the descending aorta. The final angiogram demonstrated a good result.