A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of delta(6,7)-taxane derivatives

Chem Pharm Bull (Tokyo). 2002 Oct;50(10):1398-400. doi: 10.1248/cpb.50.1398.

Abstract

A new method for the synthesis of 7-deoxytaxane analogues has been established through hydrogenation of Delta(6,7)-taxane derivatives. Among several catalysts examined, Pd-C was found to be a most effective catalyst for the preparation of target compound.

MeSH terms

  • Bridged-Ring Compounds / chemical synthesis*
  • Bridged-Ring Compounds / chemistry
  • Hydrogenation
  • Taxoids*

Substances

  • Bridged-Ring Compounds
  • Taxoids
  • taxane