GENIE: estimating demographic history from molecular phylogenies

O G Pybus; A Rambaut

doi:10.1093/bioinformatics/18.10.1404

GENIE: estimating demographic history from molecular phylogenies

Bioinformatics. 2002 Oct;18(10):1404-5. doi: 10.1093/bioinformatics/18.10.1404.

Authors

O G Pybus¹, A Rambaut

Affiliation

¹ Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK. [email protected]

PMID: 12376389
DOI: 10.1093/bioinformatics/18.10.1404

Abstract

GENIE implements a statistical framework for inferring the demographic history of a population from phylogenies that have been reconstructed from sampled DNA sequences. The methods are based on population genetic models known collectively as coalescent theory.

Availability: GENIE is available from http://evolve.zoo.ox.ac.uk. All popular operating systems are supported.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computer Simulation
Database Management Systems
Demography
Evolution, Molecular*
Genetics, Population / methods*
Information Storage and Retrieval / methods*
Models, Genetic*
Models, Statistical
Pedigree*
Phylogeny*
Population Dynamics
Software