Uterine leiomyoma after embolization by means of gelatin sponge particles alone: report of a case with histopathologic features

Ann Diagn Pathol. 2002 Oct;6(5):307-11. doi: 10.1053/adpa.2002.35745.

Abstract

We describe the histopathologic features of uterine leiomyoma after uterine artery embolization (UAE) in a 42-year-old woman. This patient, who was taking antiplatelet drugs for the treatment of cerebral disease, successfully underwent UAE using only gelatin sponge particles for a symptomatic uterine leiomyoma. Although menorrhagia improved moderately after the procedure, she underwent abdominal hysterectomy 11 months later because of recurrent uterine bleeding. Histopathology revealed that most of the area of the uterine leiomyoma was characterized by extensive coagulation necrosis, which support the positive result of the procedure. No significant abnormalities were noted in either the myometrium or endometrium, which also suggested that UAE using only gelatin sponge particles is an appropriate procedure to preserve the uterus. The histologic and radiologic features of this case are discussed. To the best of our knowledge, this is the first reported case of uterine leiomyoma after UAE using only gelatin sponge particles as a primary embolic agent.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Embolization, Therapeutic*
  • Female
  • Gelatin Sponge, Absorbable*
  • Humans
  • Hysterectomy
  • Leiomyoma / blood supply
  • Leiomyoma / diagnostic imaging
  • Leiomyoma / pathology*
  • Leiomyoma / surgery
  • Leiomyoma / therapy*
  • Menorrhagia / therapy
  • Necrosis
  • Radiography
  • Uterine Neoplasms / blood supply
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / pathology*
  • Uterine Neoplasms / surgery
  • Uterine Neoplasms / therapy*
  • Uterus / blood supply
  • Uterus / pathology