Comparative evaluation of NCCLS M27-A and EUCAST broth microdilution procedures for antifungal susceptibility testing of candida species

Antimicrob Agents Chemother. 2002 Nov;46(11):3644-7. doi: 10.1128/AAC.46.11.3644-3647.2002.

Abstract

A two-laboratory study was performed to evaluate the correlation between the NCCLS M27-A and EUCAST microdilution procedures for antifungal testing of Candida spp. A panel of 109 bloodstream isolates was tested against amphotericin B, flucytosine, fluconazole, and itraconazole. Overall, the agreement was 92% and the intraclass correlation coefficient was 0.90 (P < 0.05).

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Candida / drug effects*
  • Culture Media
  • Endpoint Determination
  • Microbial Sensitivity Tests / methods*
  • Reproducibility of Results

Substances

  • Antifungal Agents
  • Culture Media