A case of paroxysmal kinesigenic dyskinesia with spastic paraparesis

Neurol Res. 2002 Oct;24(7):684-6. doi: 10.1179/016164102101200582.

Abstract

We report the first case of paroxysmal kinesigenic dyskinesia (PKD) with spastic paraparesis. A 17-year-old male began to show a dystonic posture in both his upper limbs when walking at age 12 years. Neurological examination revealed bilateral talipes cavus, spasticity in all extremities with general hyperreflexia and pathological reflexes. On starting to walk, he showed a dystonic posture in bilateral maniphalanx, wrists, elbows, and toes. Magnetic resonance imaging (MRI) revealed high T2-weighted signal intensity in bilateral pyramidal tract. Although the combination of pyramidal and the basal ganglia disorders is very rare, the present case suggests an inter-relation of the pyramidal and the basal ganglia systems.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anticonvulsants / therapeutic use
  • Basal Ganglia / pathology
  • Basal Ganglia / physiopathology*
  • Carbamazepine / therapeutic use
  • Chorea / complications*
  • Chorea / pathology
  • Chorea / physiopathology
  • Electromyography
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Muscle Contraction / physiology
  • Muscle, Skeletal / innervation
  • Muscle, Skeletal / physiopathology
  • Paraparesis, Spastic / complications*
  • Paraparesis, Spastic / pathology
  • Paraparesis, Spastic / physiopathology
  • Pyramidal Tracts / pathology
  • Pyramidal Tracts / physiopathology*
  • Treatment Outcome

Substances

  • Anticonvulsants
  • Carbamazepine