Dysphagia in Crohn's disease: a diagnostic challenge

Dig Liver Dis. 2002 Sep;34(9):660-4. doi: 10.1016/s1590-8658(02)80210-9.

Abstract

Dysphagia is a rare manifestation in a patient with Crohn's disease. We report on the case of a patient with long-standing Crohn's disease who developed progressive dysphagia over 3 years. Endoscopy showed minimal distal oesophagitis with non-specific histological findings. Further investigation with cinematography, barium swallow and manometry established an achalasia-like motility disorder. Biopsies obtained from the oesophagus were non-specific. Balloon dilatation was performed. Initial success was followed by recurrent dysphagia. At repeat endoscopy, an oesophageal fistula was detected. An attempt at conservative medical management failed and oesophagectomy was successfully performed. Pathology results of the resected specimen confirmed the suspected diagnosis of oesophageal Crohn's disease. Even if achalasia is suspected in a Crohn's patient, it should be taken into consideration that the motility disorder could be the result of a transmural inflammation with or without fibrosis caused by Crohn's disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Catheterization
  • Crohn Disease / complications*
  • Crohn Disease / physiopathology
  • Deglutition Disorders / etiology*
  • Diagnosis, Differential
  • Endoscopy, Gastrointestinal
  • Esophageal Achalasia / diagnosis
  • Esophageal Achalasia / etiology*
  • Esophageal Fistula / diagnosis*
  • Esophageal Fistula / etiology
  • Esophageal Fistula / surgery
  • Esophagectomy
  • Esophagitis / diagnosis
  • Esophagitis / etiology
  • Humans
  • Male
  • Manometry