Remission of lymphoma after drug withdrawal in rheumatoid arthritis

Med J Aust. 2002 Nov 4;177(9):500-1. doi: 10.5694/j.1326-5377.2002.tb04919.x.

Abstract

A 63-year-old man with rheumatoid arthritis presented with pain and swelling of his right buttock. Imaging and tissue biopsy revealed a diffuse large B-cell, non-Hodgkin's lymphoma. The disease-modifying drugs he was taking, cyclosporin and methotrexate, were stopped, and the lymphoma resolved spontaneously without the use of chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / drug therapy*
  • Buttocks
  • Cyclosporine / administration & dosage*
  • Cyclosporine / adverse effects
  • Drug Therapy, Combination
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Immunosuppressive Agents / adverse effects
  • Lymphoma, B-Cell / complications
  • Lymphoma, B-Cell / diagnosis
  • Lymphoma, B-Cell / pathology*
  • Lymphoma, Large B-Cell, Diffuse / complications
  • Lymphoma, Large B-Cell, Diffuse / diagnosis
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Male
  • Methotrexate / administration & dosage*
  • Methotrexate / adverse effects
  • Middle Aged
  • Muscle Neoplasms / complications
  • Muscle Neoplasms / pathology
  • Muscle, Skeletal / pathology
  • Remission, Spontaneous

Substances

  • Immunosuppressive Agents
  • Cyclosporine
  • Methotrexate