Case report. Severe cutaneous ulceration secondary to cytomegalovirus inclusion disease during successful immune reconstitution with HAART

Nadeem A Qazi; John F Morlese; John C Walsh; Christopher B Bunker; Nicholas Francis; Mark R Nelson

Case report. Severe cutaneous ulceration secondary to cytomegalovirus inclusion disease during successful immune reconstitution with HAART

AIDS Read. 2002 Oct;12(10):452-4, 456-7.

Authors

Nadeem A Qazi¹, John F Morlese, John C Walsh, Christopher B Bunker, Nicholas Francis, Mark R Nelson

Affiliation

¹ Kobler Clinic, St. Stephen's Centre, Chelsea & Westminster Hospital, London, UK.

PMID: 12408103

Abstract

Restoration of the immune system following HAART is not without its adverse effects. We describe a case of severe cutaneous ulceration secondary to cytomegalovirus (CMV) infection in an HIV-1-seropositive man following the initiation of HAART in the absence of active CMV retinitis and discuss the likely mechanisms associated with its development.

Publication types

Case Reports

MeSH terms

Adult
Antiretroviral Therapy, Highly Active / adverse effects*
CD4-Positive T-Lymphocytes / drug effects*
Cytomegalovirus Infections / complications*
Cytomegalovirus Infections / drug therapy
Cytomegalovirus Infections / pathology
HIV Infections / complications*
HIV Infections / drug therapy
HIV Infections / immunology
Humans
Immunity, Cellular / drug effects
Male
Skin Diseases, Viral / complications*
Skin Diseases, Viral / drug therapy
Skin Diseases, Viral / pathology
Skin Ulcer / drug therapy
Skin Ulcer / etiology*