Recombinant single-chain and disulfide-stabilized Fv immunotoxins for cancer therapy

Methods Mol Biol. 2003:207:255-68. doi: 10.1385/1-59259-334-8:255.
No abstract available

MeSH terms

  • Animals
  • Disulfides / chemistry*
  • Drug Design
  • Genetic Engineering / methods*
  • Humans
  • Immunoglobulin Fragments / chemistry
  • Immunoglobulin Fragments / immunology
  • Immunoglobulin Variable Region / chemistry
  • Immunoglobulin Variable Region / immunology
  • Immunotoxins / chemistry
  • Immunotoxins / therapeutic use*
  • Mice
  • Neoplasms / immunology
  • Neoplasms / therapy*
  • Plasmids
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / isolation & purification*
  • Recombinant Proteins / pharmacology*
  • Recombinant Proteins / therapeutic use

Substances

  • Disulfides
  • Immunoglobulin Fragments
  • Immunoglobulin Variable Region
  • Immunotoxins
  • Recombinant Proteins
  • immunoglobulin Fv