Abstract
The high failure rate of amphotericin B-based therapy in patients with Aspergillus nidulans infections may not be entirely a result of host factors as suggested previously. Innate resistance of A. nidulans to polyenes may contribute to the poor response in patients.
MeSH terms
-
Amphotericin B / pharmacology*
-
Amphotericin B / therapeutic use
-
Antifungal Agents / pharmacology*
-
Antifungal Agents / therapeutic use
-
Aspergillosis / drug therapy
-
Aspergillosis / microbiology
-
Aspergillus nidulans / drug effects*
-
Aspergillus nidulans / isolation & purification
-
Drug Resistance, Microbial*
-
Humans
-
Microbial Sensitivity Tests
-
Treatment Outcome
Substances
-
Antifungal Agents
-
Amphotericin B