Perfusion MRI abnormalities in the absence of diffusion changes in a case of moyamoya-like syndrome in neurofibromatosis type 1

Neuroradiology. 2002 Nov;44(11):938-41. doi: 10.1007/s00234-002-0836-5. Epub 2002 Sep 14.

Abstract

We report on a 12-year-old boy with neurofibromatosis type 1 who suffered a transient ischemic attack. Angiography revealed occlusion of intracranial arteries, moyamoya vessels and leptomeningeal collaterals. The conventional T2-weighted and the diffusion-weighted MRI images demonstrated no pathology. Dynamic first-pass postgadolinium T2* perfusion-weighted MRI depicted altered hemodynamics in the vascular territory of the left middle cerebral artery, which defined this region as ischemic tissue at risk. The patient suffered a repeat transient ischemic attack 5 days later.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Angiography
  • Child
  • Diffusion Magnetic Resonance Imaging
  • Humans
  • Ischemic Attack, Transient / etiology
  • Male
  • Moyamoya Disease / diagnosis*
  • Moyamoya Disease / etiology
  • Neurofibromatosis 1 / complications*