[Fundic endocrine tumors and atrophic gastritis: the value of antrectomy]

Gastroenterol Clin Biol. 2002 Aug-Sep;26(8-9):782-5.
[Article in French]

Abstract

We report two cases of fundic endocrine tumors associated with fundic atrophic gastritis-related hypergastrinemia and treated by antrectomy. About twenty infracentimetric tumors were observed in each patient and restrictively involved fundic mucosa. Antrectomy induced normalization of gastrinemia and the disappearance of fundic tumors, as soon as the 4(th) and 7(th) month. No recurrence was observed during the 5-year and 18-month follow-up time, respectively. We therefore consider that antrectomy may be regarded as a useful alternative treatment in the management of atrophic gastritis-related fundic endocrine tumors.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Abdominal Pain / etiology
  • Adult
  • Biopsy
  • Carcinoid Tumor / classification
  • Carcinoid Tumor / diagnosis
  • Carcinoid Tumor / etiology*
  • Carcinoid Tumor / surgery*
  • Dyspepsia / etiology
  • Enterochromaffin-like Cells
  • Female
  • Follow-Up Studies
  • Gastrectomy / methods*
  • Gastric Fundus / surgery*
  • Gastrins / blood
  • Gastritis, Atrophic / complications*
  • Gastritis, Atrophic / pathology
  • Gastroscopy
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Pyloric Antrum / surgery*
  • Stomach Neoplasms / blood
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / etiology*
  • Stomach Neoplasms / surgery*
  • Treatment Outcome

Substances

  • Gastrins