Oral, facial, digital, vertebral anomalies with psychomotor delay: a mild form of OFD type Gabrielli?

Am J Med Genet. 2002 Dec 1;113(3):291-4. doi: 10.1002/ajmg.10815.

Abstract

A girl with oral, facial, and digital anomalies presented at birth with a large cleft palate filled by a nasopharyngeal mass and was found later to have several vertebral anomalies and mental retardation. A similar phenotype has been previously reported in a sporadic male patient [Gabrielli et al., 1994: Am J Med Genet 53:290-293], suggesting a new variant form of oral-facial-digital syndrome.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Abnormalities, Multiple / physiopathology
  • Brain / pathology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Neck / pathology
  • Psychomotor Disorders / genetics*
  • Psychomotor Disorders / physiopathology
  • Tomography, X-Ray Computed