Options available--from start to finish--for obtaining data from DNA microarrays II

Nat Genet. 2002 Dec:32 Suppl:481-9. doi: 10.1038/ng1030.

Abstract

Microarray technology has undergone a rapid evolution. With widespread interest in large-scale genomic research, an abundance of equipment and reagents have now become available and affordable to a large cross section of the scientific community. As protocols become more refined, careful investigators are able to obtain good quality microarray data quickly. In most recent times, however, perhaps one of the biggest obstacles researchers face is not the manufacture and use of microarrays at the bench, but storage and analysis of the array data. This review discusses the most recent equipment, reagents and protocols available to the researcher, as well as describing data analysis and storage options available from the evolving field of microarray informatics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • DNA / analysis*
  • DNA, Complementary / genetics
  • Data Collection / methods*
  • Forecasting
  • Genome, Human
  • Humans
  • Information Storage and Retrieval*
  • Medical Informatics / trends
  • Oligonucleotide Array Sequence Analysis / methods*
  • Quality Control
  • Research Design
  • Sequence Analysis, DNA
  • Statistics as Topic

Substances

  • DNA, Complementary
  • DNA