Abstract
Renal cell carcinomas in children are extremely rare and are usually associated with specific chromosomal rearrangements, different from those seen in adult patients. We present the case of a 9-year-old girl with a renal cell carcinoma with t(X;17) diagnosed at our institution. We also review the pertinent literature, with an emphasis on the genetic and molecular aspects associated with this rare neoplasm.
MeSH terms
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Biomarkers, Tumor / analysis
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Carcinoma, Renal Cell / chemistry
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Carcinoma, Renal Cell / genetics*
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Carcinoma, Renal Cell / pathology
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Carcinoma, Renal Cell / surgery
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Child
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Chromosome Aberrations
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Chromosome Banding
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Chromosomes, Human, Pair 17 / genetics*
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Chromosomes, Human, X / genetics*
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Female
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Genotype
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Humans
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Immunohistochemistry
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Karyotyping
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Kidney Neoplasms / chemistry
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Kidney Neoplasms / genetics*
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Kidney Neoplasms / pathology
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Kidney Neoplasms / surgery
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Phenotype
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Translocation, Genetic*
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Treatment Outcome