Abstract
In a man with osteoarthritis of the knee, Actinomyces naeslundii septic arthritis developed after intra-articular injection of hyaluronate. Actinomyces is an anaerobic Gram-positive rod. The outcome was favorable after treatment with two antibiotics and arthroscopy. The nature of the organism and its location to a joint are unusual features of this case, which illustrates the need to search for a septic complication before accepting a diagnosis of inflammation related to hyaluronate injection.
MeSH terms
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Actinomyces / isolation & purification*
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Actinomycosis / complications
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Actinomycosis / pathology*
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Actinomycosis / therapy
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Aged
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Amoxicillin / therapeutic use
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Arthritis, Infectious / etiology
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Arthritis, Infectious / pathology*
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Drug Therapy, Combination
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Humans
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Hyaluronic Acid / administration & dosage
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Hyaluronic Acid / therapeutic use
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Injections, Intra-Articular
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Knee Joint / microbiology
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Knee Joint / pathology
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Male
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Osteoarthritis, Knee / complications
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Osteoarthritis, Knee / drug therapy
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Osteoarthritis, Knee / pathology*
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Rifampin / therapeutic use
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Treatment Outcome
Substances
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Amoxicillin
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Hyaluronic Acid
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Rifampin